[PDF] Tissue Engineering of Vascular Prosthetic Grafts Peter Zilla, Howard P. Greisler

This book is about the perfect vascular graft: A hypothetical discussion of what it is and how one may go about producing it. In spite of ongoing biomaterials research, synthetic small diameter vascular prostheses still perform significantly worse than autologous vein grafts. The main reason for this disappointing situation lies in the incompleteness of healing of current grafts in humans. Even after decades of implantation, surfaces remain free of endothelium. By exploring some basic biological areas and introducing the background of clinical and pathological failures and demands, this book shall serve as a comprehensive guide, furthering the research initiatives of academic vascular surgeons, scientists and industry researchers.